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Similac Total Comfort vs Up&Up Premium
In independent testing, Up&Up Premium showed lower heavy-metal levels overall (purity 96 vs 68). The full lab numbers, metal by metal:
| Purity score | 68C | 96A |
| Lead ppb | 2.7 | — |
| Inorganic Arsenic ppb | 6 | — |
| Total Arsenic ppb | 8 | — |
| Aluminum ppb | 740 | 191 |
| Price | $1.04/oz | $0.72/oz |
| Est. cost at 28 oz/day | $4.52/day | $3.14/day |
| Origin | US | US |
| Base | Cow's milk | Cow's milk |
| Buy | Buy |
SimilacTotal Comfort
Up&UpPremium
Lab data: Consumer Reports independent testing, March 2025. Purity scores are relative to the tested cohort — methodology. Not medical advice; consult your pediatrician.