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Head to head
Similac NeoSure vs Similac Total Comfort
In independent testing, Similac Total Comfort showed lower heavy-metal levels overall (purity 68 vs 56). The full lab numbers, metal by metal:
| Purity score | 56C | 68C |
| Lead ppb | 3.5 | 2.7 |
| Inorganic Arsenic ppb | 8.7 | 6 |
| Total Arsenic ppb | 9 | 8 |
| Aluminum ppb | 799 | 740 |
| Price | $1.62/oz | $1.04/oz |
| Est. cost at 28 oz/day | $7.05/day | $4.52/day |
| Origin | US | US |
| Base | Cow's milk | Cow's milk |
| Buy | Buy |
SimilacNeoSure
SimilacTotal Comfort
Lab data: Consumer Reports independent testing, March 2025. Purity scores are relative to the tested cohort — methodology. Not medical advice; consult your pediatrician.