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Head to head
Similac Advance vs Similac Total Comfort
In independent testing, Similac Advance showed lower heavy-metal levels overall (purity 88 vs 68). The full lab numbers, metal by metal:
| Purity score | 88A | 68C |
| Lead ppb | 2 | 2.7 |
| Inorganic Arsenic ppb | — | 6 |
| Total Arsenic ppb | — | 8 |
| Aluminum ppb | 144 | 740 |
| Price | $0.81/oz | $1.04/oz |
| Est. cost at 28 oz/day | $3.53/day | $4.52/day |
| Origin | US | US |
| Base | Cow's milk | Cow's milk |
| Buy | Buy |
SimilacAdvance
SimilacTotal Comfort
Lab data: Consumer Reports independent testing, March 2025. Purity scores are relative to the tested cohort — methodology. Not medical advice; consult your pediatrician.